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Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control
Van den Berghe G, Wouters PJ, Bouillon R, et al. Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Critical Care Medicine. 2003;31(2):359–366.

This article identifies metabolic control as the strongest contributor to the improved outcomes associated with intensive insulin therapy.



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